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G-Tube Blockage Blaster
Tech ID: D2021-37 Background Gastronomy Tubes (G-Tube) are surgically implanted medical devices that create an access point to a patient’s stomach through a tube. Patients who have difficulty swallowing need G-tubes to get proper nutrition, hydration, and medications. Conditions, such as dementia, head injury, and cancer may cause swallowing...
Female Catheter Guide
Project ID D2021-33 Female urethral catheterization is an often difficult procedure and requires good use of both hands, good knowledge of anatomy, and good handling and manipulation of the catheter. Improper catheterization may result in the waste of catheters, catheter contamination, and possible patient infection. The difficulty of the procedure...
Size Adjustable Aortic Endograft Fenestration Device
Project ID: D2021-31 Background: Every year, about 200,000 people in the United States are diagnosed with an abdominal aortic aneurysm (AAA). In general, endovascular aortic aneurysm repair (EVAR) is the standard of care for AAA. However, about 20-30% of AAA patients are not eligible for standard EVAR. People who are not candidates for EVAR can be...
Smart Exosomes Enable Active Pdac Targeting and Evading Mononuclear Phagocycotic System
Project ID: D2021-13 Background: Patients affected by pancreatic ductal adenocarcinoma (PDAC), an aggressive type of cancer, have a 5-year survival rate of 9%, the lowest of any cancer in the US. Therapies for pancreatic cancer are largely hindered by the lack of an effective delivery system. Exosomes are emerging as promising nanocarriers for genes...
Solid Phantom Device for Beam Scanning
Project ID:D2021-29 Radiation therapy is a common curative procedure to treat cancer. The goal of radiation therapy is to expose the tumor to a sufficient dose of radiation so as to eradicate all cancer cells. The radiation dose is often close to the tolerance level of the normal body tissues. It is, therefore, necessary to determine the dosage levels...
Methods of Treating Cancer and Ischemia Diseases by Inhibition and Intervention of ATR Prolyl Isomerization
Project ID: D2021-42 Background: Cell death and immortality are closely associated with cancer and cancer therapeutics, as oncogenesis requires a compromise of apoptosis while most cancer therapies depend on apoptopsis. Precise regulation of programmed cell death (apoptosis) is essential for cellular and organ homeostasis. Hyperactive apoptosis is...
Three-way urology catheter stopcock
Project ID: D2021-28 Background The United States Pharmacopeial Convention has published the standard, USP 800, for handling hazardous drugs in healthcare settings. The National Institute for Occupational Safety and Health (NIOSH) has recommended that caregivers use an effective Closed System Transfer Device (CSTD) in order to minimize exposure to...
Emulsion Formation using corona discharge and electrohydrodynamic pumping
Project ID: D2020-22 Background Making water-in-oil emulsions often requires high pressure, ultrasonication, or sensitive inversion techniques that may still only result in a semi-stable colloid. In addition to emulsion shelf life, these techniques have drawbacks, such as having high-energy consumption and narrow/sensitive production parameters, needing...
Bioactive Fusion Device
Project ID: D2013-82 Background Over 650,000 spine surgeries are performed annually in the United States, with the majority being decompressive laminectomies for spinal stenosis. Spinal stenosis is a narrowing of the spinal canal housing the spinal cord. It is generally caused by arthritis in the vertebral column and/or bulging of the intervertebral...
Bitilix: A novel antimicrobial compositions using Bacillus Subtilis
Project ID: D2019-44 Background For several decades, antibacterial products such as sprays and wipes have widespread use in our society. Current antibacterial compositions are becoming increasingly ineffective against drug resistant bacteria causing more hospital-acquired infections and quickening the deaths of immunocompromised patients. The 2020...
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