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Telestroke Eye Examination Accessory
Project ID: D2019-08Background:With more than 17 million deaths annually, Stroke is a leading cause for adult disability. About 87 percentage are made up by acute ischemic stroke that occur due to obstruction of blood vessels are triaged via telemedicine. Some strokes are present with visual symptoms or vertigo with visual disturbances. However, it...
Novel Surgical Instrument Sleeve System
Project ID: D2019-29Background:Surgical instruments are designed to perform various surgical procedures and sutures are used to close the edges of incision or wounds or to repair damage tissues. During certain surgical procedures, often surgeons uses forceps to manipulate tissue and to align the tissue for passage of the needle. However, due to the...
Pyrrole-Based Composites for Metal Extraction and Analysis
Project ID#: D2018-57Invention DescriptionThe researchers at the University of Toledo have developed a chelating polypyrrole powder that can be used for filtration by directly mixing with samples and passing the sample through a filter. Desorption is then accomplished by simply dropping the pH. Applications• Selective microextraction de...
Magnetic Ionic Liquids Based Extraction and Purification of Nucleic Acids
Project ID # D2014-41Background:With a market of $3 billion in 2018 growing at a CAGR of 9.6 %, the nucleic acid isolation and extraction is one of the complex achievements in modern science. The analysis of deoxyribonucleic acid (DNA) plays a central role in a variety of applications such as determining microbial diversity in environmental samples...
Sensor for detection of ice accumulation and liquid water content in wet snow
Project ID# D2019-13BackgroundLiquid water content (LWC) of snow is the ratio of the weight of water contained to the total weight of the wet snow. LWC of snow influences its density, adhesion to surfaces, and snow cohesiveness which determines its stability, shedding, and melting runoff. Ice build-up can fall from structures, such as bridges, cau...
Charge mosaic membranes for desalination of brackish water
Project #D2019-22Background Reverse osmosis is a common technique used in desalination; it utilizes high pressure to separate water from salt. Although this separation technique is widely used for desalination, it would be advantageous to use a membrane that allows for selective transport of salt relative to water. Charge mosaic (CM) m...
Novel compound in treating autophagy-related pathologies
Project IDs: D2015-09 and D2016-81Background:Autophagy is a self-degradation process of cellular organelles that helps defend against metabolic stress, maintain metabolic equilibrium, arbitrate cell fate decisions, and safeguard genomic stability. Deficient autophagy has been associated with over 100 diseases, and experimental enhancement of autoph...
Potent Compounds for the Treatment of Canavan Disease & Cancers
Project ID: D2016-55Invention Description:Elevated levels of N-acetylaspartate (NAA) is a major hallmark of Canavan disease (CD), which currently has no cure or standard course of treatment. Mutations in the aspA gene, which encodes aspartoacylase, render it unable to adequately catalyze the synthesis of NAA in CD patients. The Nat8l gene encodes a...
Pressure sensitive polymer films with reversible porosity
Project ID: D2018-23BackgroundPressure sensing is used in the automobile, packaging, food, and pharmaceutical industries. Commercially available pressure-sensing films rely on a reaction created when microcapsules burst upon applied pressure. However, these films only function in a limited temperature range and do not work in wet or oily environme...
Device to reduce time of radiation treatments
Project ID: D2019-19Background Success of radiation therapy for those treated on a medical linear accelerator (Linac) is dependent on accurate positioning of the patient. The current system has the on-bard imaging device (OBI), consisting of a kV source and detector, which are rigidly attached to the gantry of the Linac. The device requires the MC...
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