Search Results - Diagnostics

7 Results Sort By:
Novel Composite Sensor for Detecting Free Radicals
Project ID: D2017-31Background Reactive oxygen species (ROS) detection and measurement is frequently practiced in a broad range of medical and clinical settings. Free radicals are known to cause and/or exacerbate illnesses including cancer and neurodegenerative diseases. Currently, ROS detection includes free radical trapping and fingerprinting me...
Monoclonal IgM Antibody from Entirely Carbohydrate Construct Binds and Kills Human Tumor Cells
Project ID: D2015-13Background Truncated patterns of oligosaccharides on the surfaces of cancer cells can serve as biomarkers that help to distinguish tumor cells from healthy ones. These are known as tumor-associated carbohydrate antigens (TACAs). A significant portion of cancer antigens have been identified as TACAs. Thus TACAs can be exploited f...
Diagnostic Laryngeal Mechanosensor Stimulator
Project ID: D2015-01 Device Novelty A feedback controlled pressure output system designed to precisely deliver air stimuli to upper aero digestive tract mucosa for the evaluation of dysphagia, laryngopharyngeal reflux, aspiration potential, and obstructive sleep apnea therapy compliance. Background Dysphagia and aspiration are common in the elder...
Amine-terminated Aptamer Functionalized SPR Sensor
Project ID: D2012-07 IP Status: Provisional Application Invention novelty and description: This novel invention describes sensors for target entities having at least one amine-terminated aptamer specific to the target entity. Aptamers are artificial oligonucleotides which can serve as antibody mimics because of their high affinity and selectivity ...
Highly sensitive portable technique for detecting wide variety of biological analytes
Project ID: PHYS00304 IP Status: Issued U.S. Utility Patent 8,143,072 Invention novelty and description: Novel technology offers a sensitive and broadly applicable system to detect magneto-optical and plasmon-like resonance properties of magnetic nanoparticles (MNP), dosed MNPs and biological analytes using optical or magneto-optical reflection, t...
Novel Peptides: Effective Therapeutics for Late Stage Prostate and Other EZH2-Dependent Cancers
Project ID: D2009-27Background: Prostate cancer, the second leading cause of cancer deaths among men, largely depends upon androgens for its development and progression. The importance of the Androgen Receptor in the development of prostate cancer is demonstrated by the success of anti-androgen therapy at the early stages of prostate cancer. Hormo...
Peptide Inhibitors/Activators of Src and Src Family Kinases
Project ID: D2007-01Background:The technology may be useful as therapeutics and/or as a protomer for developing better therapeutics for treatments of cancer and other diseases in which Src and Src family kinases are either highly elevated or genetically and/or functionally reduced. These disease states include, but not limited to, leukemia, prost...