Bioactive Fusion Device


Project ID: D2013-82


Over 650,000 spine surgeries are performed annually in the United States, with the majority being decompressive laminectomies for spinal stenosis. Spinal stenosis is a narrowing of the spinal canal housing the spinal cord. It is generally caused by arthritis in the vertebral column and/or bulging of the intervertebral discs. The most common treatment for spinal stenosis involves a midline approach with a decompressive laminectomy to address the stenosis. Although highly effective in relieving pain, there is growing evidence and concern over the need for reoperation to address recurrence of symptoms related to progression of slippage at the site of decompression. Concern for slippage and need for reoperation has resulted in the development of a treatment method involving the use of motion sparing devices placed without fusion to give some ‘stiffness’. This helps to prevent further slippage while allowing some motion, avoiding excessive loading of adjacent segments and avoiding disease in the adjacent segments. These devices have been successful in limiting the progression of slippage in stable spine constructs. However, recent reports suggest instrument failure and need for revision surgery. It is also reported that adjacent segment disease continues. Furthermore, the need to utilize pedicle screw technology and dynamic systems contributes to muscle trauma morbidity. It is, thus, essential to explore alternative instrumentation.

Invention Description

Researchers at The University of Toledo have developed a bioactive device and system for fusion of two bones, two parts of a bony joint, or a bony defect such as that of the spine.    


  • The bioactive fusion device may be used in spinal stenosis procedures


  • A less invasive procedure using the fusion device developed here may reduce medical costs associated with spinal stenosis surgeries
  • The device may result in reduced slippage and re-operations
  • The device may result in comparable stabilization of the spine with minimal invasiveness

IP Status:                            Patent Issued (US 9,743,961)

Patent Information:
Medical Device
For Information, Contact:
Katherine Pollard
Licensing Associate
The University of Toledo
Vijay Goel
Anand Agarwal
David Dick
Intervertebral discs