Anti-properdin monoclonal antibody 3A3E1


Project #: D2016-44a


Antigen Specificity: Human properdin purified from human plasma


Clone: 3A3E1


Specificity: human properdin


Host species: Mouse


Reactive species: Rabbit properdin (no cross reaction with mouse or rat properdin) as determined by AP-mediated lysis of erythrocytes using serum from the mentioned species in the presence or absence of the monoclonal antibody.


Description: Monoclonal antibody that inhibits properdin function by inhibiting its ability to bind to C3b.


Applications: ELISA, Western Blot, AP50 Hemolysis Assay, Flow Cytometry


References: Blatt AZ, Saggu G, Kulkarni KV, Cortes C, Thurman JM, Ricklin D, Lambris JD, Valenzuela JG, Ferreira VP. Properdin-Mediated C5a Production Enhances Stable Binding of Platelets to Granulocytes in Human Whole Blood. J. Immunol. (2016) 196: 4671-5680.


Patent Information:
For Information, Contact:
Stephen Snider
AVP Tech Transfer
The University of Toledo
419 530 6225
Viviana Ferreira