Anti-properdin monoclonal antibody 6E11A4

Description:

Project #: D2016-44b

 

Antigen Specificity: Human properdin purified from human plasma

 

Clone: 6E11A4

 

Specificity: human properdin

 

Host species: Mouse

 

Reactive species: Rabbit properdin (no cross reaction with mouse or rat properdin) as determined by AP-mediated lysis of erythrocytes using serum from the mentioned species in the presence or absence of the monoclonal antibody.

 

Description: Monoclonal antibody that binds to properdin and inhibits properdin function by inhibiting its ability to bind to C3b.

 

Applications: ELISA, Western Blot, AP50 Hemolysis Assay, Flow Cytometry

References: Blatt AZ, Saggu G, Kulkarni KV, Cortes C, Thurman JM, Ricklin D, Lambris JD, Valenzuela JG, Ferreira VP. Properdin-Mediated C5a Production Enhances Stable Binding of Platelets to Granulocytes in Human Whole Blood. J. Immunol. (2016) 196: 4671-5680.

 

Patent Information:
Category(s):
Research Tools
For Information, Contact:
Stephen Snider
AVP Tech Transfer
The University of Toledo
419 530 6225
Stephen.Snider@utoledo.edu
Inventors:
Viviana Ferreira
Keywords:
Antibodies