Plakophilin-1 (10B2) Monoclonal Antibody

Description:

Project #:  D1995-20

 

Antigen Specificity: Plakophilin-1    

 

Clone: 10B2

 

Specificity: Reacts with the N-terminus of human plakophilin-1

 

Host species: Mouse

 

Reactive species: Human

 

Description:

Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.

 

Applications: Western blot, Immunofluorescence, Immunoprecipitation
Patent Information:
Category(s):
Research Tools
For Information, Contact:
Stephen Snider
AVP Tech Transfer
The University of Toledo
419 530 6225
Stephen.Snider@utoledo.edu
Inventors:
Margaret Wheelock
James Wahl
Keith Johnson
Keywords:
Antibodies