Search Results - joseph shapiro

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Novel Non-ATP Competitive SRC Inhibitor for Treating Cancer
Project ID: D2009-07Background:P SRC kinase inhibitors have been clinically tested on a number of cancers. These inhibitors work by interrupting SRC’s role in tumor growth, proliferation, adhesion and motility. The most common method of inhibiting SRC is through an ATP analog, blocking the ATP binding site. However, ATP analogs have relat...
Peptide Inhibitors/Activators of Src and Src Family Kinases
Project ID: D2007-01Background:The technology may be useful as therapeutics and/or as a protomer for developing better therapeutics for treatments of cancer and other diseases in which Src and Src family kinases are either highly elevated or genetically and/or functionally reduced. These disease states include, but not limited to, leukemia, prost...