Search Results - christopher trabbic

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Novel compounds and methods for exosome production
Project ID: D2017-25Background Exosomes are vesicles in the range of 30 to 120nm, which are released from mammalian cells when multi-vesicular endosomes fuse with the plasma membrane. In recent times, exosomes have been implicated in cancer. Mounting evidence suggests that exosomes play an important role in mediating intercellular communication wi...
“Thin” Molecules for Treating Obesity and Type II Diabetes
Project ID: D2016-29IP Status: PCT patent application filedInvention Description and Novelty: “Thin” molecules offer stronger binding to PPAR and include greater lipid burning and glucose lowering properties. Applications: Dyslipidemia, obesity and type II diabetes Value propositions: • Bilirubin reduces body fat percentage...
Advancement in Platinum Based Cancer Therapeutics
Project ID: D2014-33Novelty: Small drug like molecules that inhibits DNA repair factors for cisplatin (and other platinum based drugs) resistance towards solid tumors, thereby increasing cisplatin cytotoxicity and efficacy. Value proposition: One of the limitations of chemotherapy in ovarian cancer is the innate/acquired drug resistance in cancer c...