Description:
Project ID: TECH2025-15
Background
Imaging and biosensing devices are used worldwide for a wide variety of applications from research to healthcare to environmental monitoring. However, these measurements become challenging in resource-limited settings such as remote areas or villages in third-world countries. In resource-limited settings, traditional imaging and readout devices are often hard to obtain due to high costs, bulky designs, and the need for trained personnel to operate them. To say the least, there is still a need in the art for new and improved on-chip imaging systems.
Invention Description
Researchers at the University of Toledo have developed a compact, portable, user-friendly and low-cost on-chip imaging platform. Device has high resolution and sensitivity and can be used for imaging (microscope), sensing (biosensor), and counting particles (cytometer). The on-chip imaging system combines a wide field of view with high resolution and a favorable signal to noise ratio. Furthermore, the imaging system contains a CMOS sensor combined with a two-dimensional microns array to increase light collection efficiency, image resolution, and signal to noise ratio in both bright field and fluorescence microscopy. Lastly technology can also be easily implemented to become a wearable device.
Applications
- A high-resolution, portable 3-in-1 on-chip microscope, biosensor, and cytometer system
Advantages
- High Resolution and High Sensitivity (high signal to noise ratio)
- Multi modal (bright field – fluorescence)
- Portable and Low-Cost design
IP Status: Patent Pending
Key Words: On-chip, multi-modal, portable, microscope, biosensor, cytometer, direct monitoring

