Search Results - paul erhardt

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Novel compounds and methods for exosome production
Project ID: D2017-25Background Exosomes are vesicles in the range of 30 to 120nm, which are released from mammalian cells when multi-vesicular endosomes fuse with the plasma membrane. In recent times, exosomes have been implicated in cancer. Mounting evidence suggests that exosomes play an important role in mediating intercellular communication wi...
Advancement in Platinum Based Cancer Therapeutics
Project ID: D2014-33Novelty: Small drug like molecules that inhibits DNA repair factors for cisplatin (and other platinum based drugs) resistance towards solid tumors, thereby increasing cisplatin cytotoxicity and efficacy. Value proposition: One of the limitations of chemotherapy in ovarian cancer is the innate/acquired drug resistance in cancer c...
Novel Method to Prepare Isoflavene and Chromane Analogs
Project ID: D2011-60Novelty: A practical and novel intramolecular wittig reaction procedure for the production of variously substituted isoflavene and chromane analogs. Value proposition: Development of safe and economic manufacturing processes for natural product derivatives have always been a priority in the industry. Isoflavene systems require t...