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Osteoanabolism by 14-3-3zeta
Project ID: D2021-48 Background Bone loss is one of the common symptoms associated with normal aging and pathologies. An increased bone mass loss and mineral density are the primary reason for osteoporosis, arthritis, fractures, etc. Together it affects millions of individuals in the US alone. While several drugs targeting the prevention of bone...
Therapeutic and Prophylactic for Arthritis
Project ID: D2019-15Background Rheumatoid Arthritis (RA) is an
autoimmune
disease that causes swelling of the joints. Treatments are limited to anti-inflammatories, DMARDs, corticosteroids or biologics. Genetic research has identified several genetic factors that determine susceptibility to developing RA. However, there are no prophylactics or therapeutics...
Topical Treatment for Raynaud’s Phenomenon Targets Cold Receptor
Project ID: D2015-43IP Status: PCT Patent application Invention Description and Novelty: Systemic sclerosis (also known as scleroderma, SSc) is an
autoimmune
connective tissue disease that is characterized by the presence of Raynaud’s phenomenon (RP) that manifests by repeated episodes of vasospasm of the distal arteries...