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Osteoanabolism by 14-3-3zeta
Project ID: D2021-48 Background Bone loss is one of the common symptoms associated with normal aging and pathologies. An increased bone mass loss and mineral density are the primary reason for osteoporosis,
arthritis
, fractures, etc. Together it affects millions of individuals in the US alone. While several drugs targeting the prevention of bone...
Therapeutic and Prophylactic for
Arthritis
Project ID: D2019-15Background Rheumatoid
Arthritis
(RA) is an autoimmune disease that causes swelling of the joints. Treatments are limited to anti-inflammatories, DMARDs, corticosteroids or biologics. Genetic research has identified several genetic factors that determine susceptibility to developing RA. However, there are no prophylactics or therapeutics...