Search Results - orthopedic

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Thermoresponsive Injectable Microparticles-Gel Composites with Low Dose of Recombinant BMP-9 and VEGF for Bone Repair

Bone repair remains a major clinical need because autograft and allograft approaches can be limited by donor-site morbidity, pain, resorption, disease-transmission risk, and immune rejection. Tissue-engineered alternatives seek to combine osteoconductive scaffolds, osteoinductive factors, and regenerative cells, but many scaffold systems require invasive...

Fixation and Reconstruction System for Ankle Fractures

Project ID: D2018-27Background Syndesmotic Ankle fractures are common, and sometimes challenging to treat clinically. These fractures are a common source of substantial patient morbidity. It is estimated that about 290,000 people suffer syndesmotic ankle injuries every year in the United States. Devices that are currently used to treat these ankle...

External Locking Fixation for Tibia Fractures

Project ID: D2018-25 Extra-articular tibia fractures which include proximal tibia, diaphysis and distal tibia fractures are often associated with many serious complications and result in disability. Current treatment methods include the use of an intramedullary rod, an internal locking/unlocking plate, and an external fixator. However, these treatment...

A Novel Process to Coat Implant Surfaces with Bi-Functional Bioactive Antibacterial Coatings

Project ID: D2017-07Background In the orthopedic field, there is a need for improved capabilities for creating strong osseointegration at bone-implant interfaces and treating bacterial infections. Implant-related infections occur in 0.75% in hip implants and 1.5% in knee implants resulting in reduced lifespan and increased failure rate of prosthesis,...