Micropatterned Silicone Oxygenating Dressing For Chronic Wounds


Project ID: D2018-09



Wound healing requires oxygen, moisture, and pressure offloading. It is difficult to simultaneously obtain these conditions because oxygen has a low diffusivity in water. Hyperbaric oxygen therapy (HBOT) is an approved treatment which uses a pressurized chamber to increase oxygen absorption. However, patients must be ambulatory and complete a series of 30-60 sessions, each lasting about 2 hours. Additionally, HBOT chambers are not available everywhere and treatments cost between $15,000 and $40,000 over the duration of the treatment. Therefore, there is a need for an affordable and mobile treatment option to treat chronic wounds.


Invention Description

Researchers at the University of Toledo have developed a wound dressing capable of oxygen diffusion while still maintaining the moist environment ideal for healing. A microfabricated oxygen-permeable material is specially designed to maximize oxygen delivery. 



•       Oxygenating dressing for chronic wounds

•       Available to those who are not eligible for hyperbaric treatment



•       Available to those who are not eligible for hyperbaric treatment or immobile

•       Can be used in the comfort of a patient’s home and therefore, extend the treatment beyond two hours

•       Does not require the use of deep reactive ion etching/expensive manufacturing methods

•       More affordable than HBOT


IP Status:       Patent Pending


Publication:       Jaeger A, Das D, Morgan N, Pursley R, McQueen P, Hall M, Pohida T, Gottesman M.  Microfabricated polymeric vessel mimetics for 3-D cancer cell culture Biomaterials. 2013 Nov; 34(33): 8301-8313.


Patent Information:
For Information, Contact:
Katherine Pollard
Licensing Associate
The University of Toledo
Chandan Das
Munier Nazzal
F. Charles Brunicardi
Diabetic ulcers
Hyperbaric oxygen treatment
Wound healing