Search Results - william+messer

1 Results

Sort By:

Allosteric Modulation of Muscarinic Acetylcholine Receptor for Treatment of Neurological Disorders

Project ID: D2022-18 Background Muscarinic acetylcholine receptors (mAChRs) are G protein-coupled receptors that are located in the cell membranes of neurons and mediate the effects of the neurotransmitter acetylcholine (ACh). Each mAChR forms a complex with intracellular G proteins that, when activated, produce an intracellular signaling cascade....