Search Results - william+messer

2 Results

Sort By:

Allosteric Modulation of Muscarinic Acetylcholine Receptor for Treatment of Neurological Disorders

Project ID: D2022-18 Background Muscarinic acetylcholine receptors (mAChRs) are G protein-coupled receptors that are located in the cell membranes of neurons and mediate the effects of the neurotransmitter acetylcholine (ACh). Each mAChR forms a complex with intracellular G proteins that, when activated, produce an intracellular signaling cascade....

Muscarinic Agonists for the Treatment of Autism Spectrum Disorder

Project ID: D2011-54Background Autism Spectrum Disorder (ASD) describes a group of developmental disorders that is often characterized by persistent repetitive and restrictive behaviors and deficits in social communication that, overall, affect the ability of the individual to functional normally in a social setting. Although early treatment and care...