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Immunostimulatory adjuvant molecules and antibody recruiting molecule-containing lipopeptide vaccines
Project ID: D2017-06Background Protein conjugate vaccines have limitations due to the innate immunogenicity of carrier proteins that can suppress the response against associated antigens. Thus, the development of fully synthetic vaccines have been under intense investigation in the last decade in immunotherapy. A typical fully synthetic vaccine in...
“Sweet-P”: Molecule for Targeting Human Glucocorticoid Receptor Beta in Cancer
Project ID: D2016-49Background Glucocorticoids are the most prescribed anti-inflammatory drugs. They are also used in cancer therapies, and for their protective properties against the toxic effects of chemotherapy. Glucocorticoids may, however, cause resistance to platinum-based chemotherapeutics, resulting in the proliferation of cancer cells. The...