Search Results - steven+sucheck

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Enhanced Immunogenicity Vaccine Development Platform

Project ID: D2012-14BackgroundExtensive research is being carried out globally to develop vaccines for the treatment of different types of infections and diseases. However, improved immunogenicity and efficient delivery of antigens to the antigen producing cells (APCs) via these vaccines is still a challenge. Also, it is very costly and time consuming...

Novel Isoselenazolone Derivatives Show Effectiveness Against Multiple Human Disease-causing Pathogens

Project ID: D2015-17Invention Description:Neurodegenerative, inflammatory and other physiological diseases are linked to the activity of reactive oxygen species (ROS). Glutathione peroxidase is a Selenium-based enzyme that has been shown to protect biomembranes and other cellular components from damage caused by ROS, by scavenging hydrogen peroxide...

Immunostimulatory adjuvant molecules and antibody recruiting molecule-containing lipopeptide vaccines

Project ID: D2017-06Background Protein conjugate vaccines have limitations due to the innate immunogenicity of carrier proteins that can suppress the response against associated antigens. Thus, the development of fully synthetic vaccines have been under intense investigation in the last decade in immunotherapy. A typical fully synthetic vaccine includes...

Anti-Infective Antibacterial Agents against Mycobacterium Tuberculosis and other Mycobacterium Species

Project ID: D2016-53 Background Mycobacterium tuberculosis is an acid-fast gram-positive bacterium that causes tuberculosis (TB). TB ranks first for the number of deaths in humans caused by an infectious agent. It has been difficult to eradicate TB even though the infection is treatable. Treatment for TB takes at least 6 months and, sometimes, up...