Search Results - shi-he+liu

3 Results

Sort By:

Smart Exosomes Enable Active Pdac Targeting and Evading Mononuclear Phagocycotic System

Project ID: D2021-13 Background: Patients affected by pancreatic ductal adenocarcinoma (PDAC), an aggressive type of cancer, have a 5-year survival rate of 9%, the lowest of any cancer in the US. Therapies for pancreatic cancer are largely hindered by the lack of an effective delivery system. Exosomes are emerging as promising nanocarriers for genes...

Fully automated fraction collection instrument

Project ID: TECH-2023-10 Background Size exclusion chromatography (SEC) is the preferred method to isolate and purify exosomes and extracellular vesicles. However, this technique is labor-intensive, requiring the operator to pipette samples, buffer, and wash into individual columns. Current solutions attempt to automate fraction collection, but still...

Targeting LASP1, eIF4A1, eIF4B, and CXC4 with Modulators for treating cancer

Project ID: D2019-32 Background: Breast cancer (BC) is a heterogeneous disease and is the second leading cause of death in women among the cancer mortalities. With the new estimates in 2019, 3 out of 10 women will develop BC in her lifetime and 1 in 7 will succumb to BC. Mortality in BC patients is mainly due to metastasis to the lungs, bone, and brain....