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Fluorescent labeling and B cell phenotyping of PPS specific B cells
Project ID: D2011-08 Description: The phenotype of B cells responsible for the production of anti-pneumococcal polysaccharide antibody has been unclear. Although individuals that respond poorly to the 23-valent
pneumococcal polysaccharide (PPS)
vaccine, Pneumovax, are profoundly deficient or lack IgM memory cells (CD27+IgM+), they are also deficient...