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Novel Epothilone Analogues as Antileukemia Agents and Method Thereof
Project ID: PHR00107 Novelty: Conformationally restrained novel epothilone analogue exhibiting strong and selective growth inhibitory effect on leukemia cell lines. Background: Epothilones have been reported to exhibit potent anticancer activity and a number of epothilone analogs have entered clinical evaluation in humans (in addition to Epo B),...