Search Results - neurodegenerative

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Novel Isoselenazolone Derivatives Show Effectiveness Against Multiple Human Disease-causing Pathogens
Project ID: D2015-17Invention Description:Neurodegenerative, inflammatory and other physiological diseases are linked to the activity of reactive oxygen species (ROS). Glutathione peroxidase is a Selenium-based enzyme that has been shown to protect biomembranes and other cellular components from damage caused by ROS, by scavenging hydrogen peroxide...
Furoxans as Novel Therapeutics for Neurodegenerative Disorders
Project ID: D2017-15Invention Description:Nitric oxide (NO) signaling is essential for brain activity and normal neuronal function. Disrupted NO signaling is implicated in several central nervous system (CNS) and neurodegenerative disorders. NO mimetics, such as nitrates, have been implicated for use against a variety of neurological disorders, in...
Use of fluorescent ANTS to examine the BBB-permeability of polysaccharide
Project ID: D2015-27Invention Description: Methods of generating and administering digestion products of FDA-approved low acyl gellan gum (LA-GAGR) to produce neuroprotective mega-GAGR, midi-GAGR, and mini-GAGR and administration thereof.Applications: Compositions comprising midi and/or mini-GAGR have been shown to be useful for treatment of neuro...
Novel agents and methods for treating neurodegenerative disorders
Project ID: D2013-69IP Status: Utility patent application filed Invention Description: Methods of generating and administering digestion products of FDA-approved low acyl gellan gum (LA-GAGR) to produce neuroprotective mega-GAGR, midi-GAGR, and mini-GAGR and administration thereof. Applications: Compositions comprising midi and/or mini-GAGR have b...