Search Results - leukemia

2 Results Sort By:
“Sweet-P”: Molecule for Targeting Human Glucocorticoid Receptor Beta in Cancer
Project ID: D2016-49Background Glucocorticoids are the most prescribed anti-inflammatory drugs. They are also used in cancer therapies, and for their protective properties against the toxic effects of chemotherapy. Glucocorticoids may, however, cause resistance to platinum-based chemotherapeutics, resulting in the proliferation of cancer cells. The...
Novel Epothilone Analogues as Antileukemia Agents and Method Thereof
Project ID: PHR00107 Novelty: Conformationally restrained novel epothilone analogue exhibiting strong and selective growth inhibitory effect on leukemia cell lines. Background: Epothilones have been reported to exhibit potent anticancer activity and a number of epothilone analogs have entered clinical evaluation in humans (in addition to Epo B),...