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Monoclonal IgM Antibody from Entirely Carbohydrate Construct Binds and Kills Human Tumor Cells

Project ID: D2015-13Background Truncated patterns of oligosaccharides on the surfaces of cancer cells can serve as biomarkers that help to distinguish tumor cells from healthy ones. These are known as tumor-associated carbohydrate antigens (TACAs). A significant portion of cancer antigens have been identified as TACAs. Thus TACAs can be exploited for...