Search Results - inhibitor

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Use of Small Molecule Inhibitors as Anti-Thrombotic Agents
Project: D2016-03IP Status: PCT filed Invention Description: Discovery of a new family of small molecules that can be used to decrease the risk of thrombosis in patients with several diseases. Novelty: The most important aspect of this new antithrombotic is that it prevents the transition of platelets to a hypersensitive state without impacting nor...
New Species-Selective Antimicrobials to Thwart Developing Resistance
Project ID: D2015-58IP Status: PCT patent application filedInvention Description and Novelty: Drug resistance limits the effectiveness of most currently used antimicrobial agents. Infectious organisms are becoming resistant to even the most recently developed antimicrobials that target essential steps in cell wall assembly and protein biosynthesis....
Method to Develop Compounds for Treating Canavan Disease
Project ID: D2016-26IP Status: PCT patent application filedInvention Description and Novelty: Canavan disease is a neurological disease caused by an interruption in the metabolism of N-acetylaspartate (NAA). Numerous mutations have been found in the enzyme that hydrolyzes NAA, and the catalytic activity of aspartoacylase is significantly impaired i...