Search Results - immunotherapy

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Immunostimulatory adjuvant molecules and antibody recruiting molecule-containing lipopeptide vaccines

Project ID: D2017-06Background Protein conjugate vaccines have limitations due to the innate immunogenicity of carrier proteins that can suppress the response against associated antigens. Thus, the development of fully synthetic vaccines have been under intense investigation in the last decade in immunotherapy. A typical fully synthetic vaccine includes...

Monoclonal IgM Antibody from Entirely Carbohydrate Construct Binds and Kills Human Tumor Cells

Project ID: D2015-13Background Truncated patterns of oligosaccharides on the surfaces of cancer cells can serve as biomarkers that help to distinguish tumor cells from healthy ones. These are known as tumor-associated carbohydrate antigens (TACAs). A significant portion of cancer antigens have been identified as TACAs. Thus TACAs can be exploited for...