Search Results - hypertension

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1,3-Butanediol as a therapeutic for kidney disease
Project ID: D2018-47Background Approximately 33 million Americans have kidney disease and over the last decade, the rate of chronic kidney disease has risen more than 25%. Kidney disease can cause additional complications including high blood pressure. For example, 80%-90% of CKD patients have high blood pressure at some point during their time wi...
Humanized Endothelial Specific TRPC3 Transgenic Mouse
Project: D2012-18 Strains: EST3Tg/C57BL6 and EST3Tg/Apoe-/- Type: Humanized transgenic mouse Background: In the U.S., atherosclerosis, hypertension and stroke are the major causes of death due to cardiovascular disease and remain most frequent vascular complications of metabolic diseases such as diabetes, obesity and metabolic syndrome. A common si...