Search Results - endothelial dysfunction

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Humanized Endothelial Specific TRPC3 Transgenic Mouse
Project: D2012-18 Strains: EST3Tg/C57BL6 and EST3Tg/Apoe-/- Type: Humanized transgenic mouse Background: In the U.S., atherosclerosis, hypertension and stroke are the major causes of death due to cardiovascular disease and remain most frequent vascular complications of metabolic diseases such as diabetes, obesity and metabolic syndrome. A common signature...
Novel Fluorescent Probe and Assay for Quantifying Adenosine and Adenosyl-Containing Compounds in Solution
Project: D2014-24Novelty: Use of a novel fluorescent probe and a recombinant protein in development of in vitro assays for determination of adenosine concentration in biochemical reactions. Description: Researchers at the University of Toledo have developed a fluorescence polarization (FP) assay that uses nanomolar concentrations of a novel fluorescent...