Search Results - chimeric+antigen+receptor

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Inducing plasticity to prime immune system for CAR-Treg therapy

Project ID: D2022-28 Background Regulatory T cells (Tregs) are the critical regulators of peripheral immune tolerance; when defective, Tregs can lead to autoimmune disorders, such as Type 1 Diabetes (T1D) A more recent approach to prevent/treat autoimmunity is to refit immune cells towards their non-inflammatory phenotype in the affected organ. Chimeric...