Search Results - alzheimer's

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Novel compound in treating autophagy-related pathologies
Project IDs: D2015-09 and D2016-81Background:Autophagy is a self-degradation process of cellular organelles that helps defend against metabolic stress, maintain metabolic equilibrium, arbitrate cell fate decisions, and safeguard genomic stability. Deficient autophagy has been associated with over 100 diseases, and experimental enhancement of autoph...
Furoxans as Novel Therapeutics for Neurodegenerative Disorders
Project ID: D2017-15Invention Description:Nitric oxide (NO) signaling is essential for brain activity and normal neuronal function. Disrupted NO signaling is implicated in several central nervous system (CNS) and neurodegenerative disorders. NO mimetics, such as nitrates, have been implicated for use against a variety of neurological disorders, in...