Search Results - Drug Delivery

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Stiff Gel Adhesives for Underwater Use
Project ID: D2014-08Background Underwater adhesion has several potential medical, household and industrial applications. Generally, underwater adhesives have been prepared using methods that rely on in situ polymerization, covalent crosslinking, or the use of highly specialized biological or biomimetic polymers. Despite current strategies, many cha...
Synthesis of Novel Calcium Phosphate Nanowhiskers
Project ID: D2011-31 Background: Viral gene delivery techniques are among the most commonly used gene delivery techniques owing to their high reported efficiencies. The primary drawback of viral gene delivery results from the risks associated with insertional mutagenesis. In some instances, such therapies have resulted in patient death after the ...
Furoxans as Novel Therapeutics for Neurodegenerative Disorders
Project ID: D2017-15Invention Description:Nitric oxide (NO) signaling is essential for brain activity and normal neuronal function. Disrupted NO signaling is implicated in several central nervous system (CNS) and neurodegenerative disorders. NO mimetics, such as nitrates, have been implicated for use against a variety of neurological disorders, in...
Monoclonal IgM Antibody from Entirely Carbohydrate Construct Binds and Kills Human Tumor Cells
Project ID: D2015-13Background Truncated patterns of oligosaccharides on the surfaces of cancer cells can serve as biomarkers that help to distinguish tumor cells from healthy ones. These are known as tumor-associated carbohydrate antigens (TACAs). A significant portion of cancer antigens have been identified as TACAs. Thus TACAs can be exploited f...