Search Results - Chemistry

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New Species-Selective Antimicrobials to Thwart Developing Resistance
Project ID: D2015-58IP Status: PCT patent application filedInvention Description and Novelty: Drug resistance limits the effectiveness of most currently used antimicrobial agents. Infectious organisms are becoming resistant to even the most recently developed antimicrobials that target essential steps in cell wall assembly and protein biosynthesis....
Anti-Infective Antibacterial Agents against Mycobacterium Tuberculosis and other Mycobacterium Species
Project ID: D2016-53IP Status: PCT patent application #PCT/US17/028782Invention Description and Novelty: New compound represents useful antimicrobial agents effective against human and veterinary pathogens, particularly acid-fast organisms such as Mycobacterium tuberculosis and shows improved efficacy and activity well below toxicity to human monoc...
Method to Develop Compounds for Treating Canavan Disease
Project ID: D2016-26IP Status: PCT patent application filedInvention Description and Novelty: Canavan disease is a neurological disease caused by an interruption in the metabolism of N-acetylaspartate (NAA). Numerous mutations have been found in the enzyme that hydrolyzes NAA, and the catalytic activity of aspartoacylase is significantly impaired i...
Novel Method to Prepare Isoflavene and Chromane Analogs
Project ID: D2011-60Novelty: A practical and novel intramolecular wittig reaction procedure for the production of variously substituted isoflavene and chromane analogs. Value proposition: Development of safe and economic manufacturing processes for natural product derivatives have always been a priority in the industry. Isoflavene systems require t...
Highly sensitive portable technique for detecting wide variety of biological analytes
Project ID: PHYS00304 IP Status: Issued U.S. Utility Patent 8,143,072 Invention novelty and description: Novel technology offers a sensitive and broadly applicable system to detect magneto-optical and plasmon-like resonance properties of magnetic nanoparticles (MNP), dosed MNPs and biological analytes using optical or magneto-optical reflection, t...