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Pranlukast for Inhibition of Oral Microbe Biofilms
Project ID:TECH2023-37 Background Streptococcus mutans is a bacterium that lives in the oral cavity of humans and is a major cause of caries, also known as dental cavities. In order to cause caries, the bacterium must form a biofilm. The biofilm creates a microenvironment in which the enamel of teeth is degraded and caries form. True anti-biofilm...
Species-specific inhibitors of methionine adenosyltransferase (MAT)
Project ID: TECH2023-31 Background Drug resistance, especially to antibiotics and other
antimicrobial
s, is a huge and growing problem. Some bacteria already have untreatable strains, and other microbes have never had good drug options. Broad-spectrum antibiotics have substantial side effects, including microbiome disruption. Cryptosporidium parvum...