Search Results - Research Tools

41 Results Sort By:
Novel Method for Reverse Automated Nucleic Acid Synthesis
Project ID: D2017-49BackgroundAutomated processes are widely used in the synthesis of modified oligonucleotide strands. These modified oligonucleotides are useful in the treatment or investigation of various conditions and diseases. Currently, the most common subunits used to synthesize RNA strands in the 3 to 5 direction are 3 phosphoramidite...
Sensor and assay for screening of photosensitizers in living cells
Project ID: D2018-33Background Photodynamic therapy (PDT) uses light and a photosensitizer in the presence of oxygen to elicit cell death. This technique has been under investigation for use in treatment of cancerMost often used to treat skin cancer, mycosis fungoides, and non-small cell lung cancer. Researchers need to detect the ability of PDTs ...
Homogenous and Reusable Superacid Polymer Catalyst for the Synthesis of 5-Hydroxymethylfurfural from Glucose
Project ID: D2018-18Background Combinations of Brønsted and Lewis acid catalysts are generally used for the production of 5-hydroxymethylfurfural (HMF) from glucose. However, reutilization of these catalysts is challenging due to their solubility in reaction medium. Heterogeneous catalysts containing both types of acid sites are not usually...
3D Printable Bioactive Glass/Polymer Composite
Project ID: D2018-16Background Popularity of 3D printing has grown exponentially in the last decade, leading to endless applications of rapid prototyping and production of parts in a variety of fields such as aerospace and medicine. In any application, it is critical that the appropriate printing material is selected to ensure proper function and ...
Novel Composite Sensor for Detecting Free Radicals
Project ID: D2017-31Background Reactive oxygen species (ROS) detection and measurement is frequently practiced in a broad range of medical and clinical settings. Free radicals are known to cause and/or exacerbate illnesses including cancer and neurodegenerative diseases. Currently, ROS detection includes free radical trapping and fingerprinting me...
Treatment of Ischemic Stroke with ROS-Sensitive Nitric Oxide Synthase Inhibitors
Project ID: D2018-11Background Nearly 800,000 people in the United States suffer a stroke every year, with about 87% of the strokes being classified as ischemic. Ischemic stroke is caused by blockage of blood flow to the brain, which results in neuronal and glial hypoxia and, subsequently, inflammatory and free radical-mediated cell death. Reactive...
Anti-Beta-Catenin (5H10) Monoclonal Antibody
Project #: D1995-12e Antigen Specificity: Beta – catenin Clone: 5H10 Specificity: Reacts with ~92 kDa β-catenin protein Host species: Mouse Reactive species: Human, Mouse, Chicken Description: 5H10 monoclonal antibody reacts with beta-catenin protein, a member of a catenin family. Catenins are intracellular proteins that interact...
Anti-properdin monoclonal antibody 1G6D2
Project #:D2016-44fAntigen Specificity: Human properdin purified from human plasmaClone: 1G6D2Specificity: human properdinHost species: MouseReactive species: UnknownDescription: Monoclonal antibody that binds to properdin, but does not inhibit its function (i.e. ability to bind to C3bApplications: ELISA, Western Blot, AP50 Hemolysis Assay, Flow Cy...
Anti-properdin monoclonal antibody 3A3E1
Project #: D2016-44aAntigen Specificity: Human properdin purified from human plasmaClone: 3A3E1Specificity: human properdinHost species: MouseReactive species: Rabbit properdin (no cross reaction with mouse or rat properdin) as determined by AP-mediated lysis of erythrocytes using serum from the mentioned species in the presence or absence of the m...
Anti-properdin monoclonal antibody 6E11A4
Project #: D2016-44bAntigen Specificity: Human properdin purified from human plasmaClone: 6E11A4Specificity: human properdinHost species: MouseReactive species: Rabbit properdin (no cross reaction with mouse or rat properdin) as determined by AP-mediated lysis of erythrocytes using serum from the mentioned species in the presence or absence of the ...
1 2 3 4 5