Search Results - Pharmaceuticals

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Topical Treatment for Raynaud’s Phenomenon Targets Cold Receptor
Project ID: D2015-43IP Status: PCT Patent application Invention Description and Novelty: Systemic sclerosis (also known as scleroderma, SSc) is an autoimmune connective tissue disease that is characterized by the presence of Raynaud’s phenomenon (RP) that manifests by repeated episodes of vasospasm of the distal a...
Unique family of trianionic ligand precursors provide unprecedented control over polymer properties
Project ID: D2009-89IP Status: U.S. Utility Patent #8,524,846 Invention Description: These trianionic ligand precursors are useful in making proprietary constrained geometry complexes (CGCs) that can potentially function as single-site homogeneous and heterogeneous catalysts. These cataly...
Use of fluorescent ANTS to examine the BBB-permeability of polysaccharide
Project ID: D2015-27Invention Description: Methods of generating and administering digestion products of FDA-approved low acyl gellan gum (LA-GAGR) to produce neuroprotective mega-GAGR, midi-GAGR, and mini-GAGR and administration thereof.Applications: Compositions comprising midi and/or mini-GAGR have been shown to be useful for treatment of neuro...
Novel agents and methods for treating neurodegenerative disorders
Project ID: D2013-69IP Status: Utility patent application filed Invention Description: Methods of generating and administering digestion products of FDA-approved low acyl gellan gum (LA-GAGR) to produce neuroprotective mega-GAGR, midi-GAGR, and mini-GAGR and administration thereof. Applications: Compositions comprising midi and/or mini-GAGR have b...
Novel agents and methods for treating metabolic bone disorders and other conditions
Project ID: D2014-15IP Status: Provisional patent #62/115,786Invention Description: Methods of generating and administering digestion products of FDA-approved low acyl gellan gum (LA-GAGR) to produce mega-GAGR, midi-GAGR, and mini-GAGR and administration thereof. Applications: Compositions comprising midi- and/or mini-GAGR have been shown to be us...
Novel HDAC Inhibitors as Anti-Cancer Agents
Project: D2014-49 Background: Cancer remains the second most common cause of death, accounting for nearly 1 out of every 4 deaths in the United States. American Chemical Society has estimated diagnosis of more than 1.6 million new cancer cases and deaths of more than 500,000 cancer patients in the US in the year 2014 alone. A promising new anticanc...
Small Molecule to Modulate Skin Pigmentation
Project ID: D2013-88Novelty: Use of selective small-molecule to reduce pigmentation in skin cells. Background: Hyperpigmentation is a common condition in which patches of skin become darker in color than the surrounding skin. Globally, it is estimated that total annual sales of skin lightening and appearance enhancing cosmeceuticals amount to more...
Amine-terminated Aptamer Functionalized SPR Sensor
Project ID: D2012-07 IP Status: Provisional Application Invention novelty and description: This novel invention describes sensors for target entities having at least one amine-terminated aptamer specific to the target entity. Aptamers are artificial oligonucleotides which can serve as antibody mimics because of their high affinity and selectivity ...
Novel Method to Prepare Isoflavene and Chromane Analogs
Project ID: D2011-60Novelty: A practical and novel intramolecular wittig reaction procedure for the production of variously substituted isoflavene and chromane analogs. Value proposition: Development of safe and economic manufacturing processes for natural product derivatives have always been a priority in the industry. Isoflavene systems require t...
Highly sensitive portable technique for detecting wide variety of biological analytes
Project ID: PHYS00304 IP Status: Issued U.S. Utility Patent 8,143,072 Invention novelty and description: Novel technology offers a sensitive and broadly applicable system to detect magneto-optical and plasmon-like resonance properties of magnetic nanoparticles (MNP), dosed MNPs and biological analytes using optical or magneto-optical reflection, t...