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Carbon Dioxide as a Directing Group for C-H Functionalization Reactions
Project ID: D2018-03Background The development of new strategies for elaboration of amines via C–H functionalization has been an important area of research over the last decade. Compounds made by this method are useful in a variety of industries, including the agrochemical and pharmaceutical industries. Numerous directing groups have been u...
Enhanced Immunogenicity Vaccine Development Platform
Project ID: D2012-14BackgroundExtensive research is being carried out globally to develop vaccines for the treatment of different types of infections and diseases. However, improved immunogenicity and efficient delivery of antigens to the antigen producing cells (APCs) via these vaccines is still a challenge. Also, it is very costly and time consum...
Immunostimulatory adjuvant molecules and antibody recruiting molecule-containing lipopeptide vaccines
Project ID: D2017-06Background Protein conjugate vaccines have limitations due to the innate immunogenicity of carrier proteins that can suppress the response against associated antigens. Thus, the development of fully synthetic vaccines have been under intense investigation in the last decade in immunotherapy. A typical fully synthetic vaccine in...