Search Results - Bioengineering

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Fixation and Reconstruction System for Ankle Fractures
Project ID: D2018-27Background Syndesmotic Ankle fractures are common, and sometimes challenging to treat clinically. These fractures are a common source of substantial patient morbidity. It is estimated that about 290,000 people suffer syndesmotic ankle injuries every year in the United States. Devices that are currently used to treat these ankle...
External Locking Fixation for Tibia Fractures
Project ID: D2018-25Background Extra-articular tibia fractures which include proximal tibia, diaphysis and distal tibia fractures are often associated with many serious complications and result in disability. Current treatment methods include the use of an intramedullary rod, an internal locking/unlocking plate, and an external fixator. However, t...
Loading Platform for Three-Dimensional Tissue Engineering Scaffolds
Project ID: D2016-48 IP Status: PCT patent application # PCT/US17/020706 Applications: Three-dimensional loading platform for mechanical stimulation of cellular scaffolds for pharmaceuticals and tissue engineering strategies.Invention Description and Novelty: Innovative method of handling and transfer of mechanical strains to tissue engineering sc...
Process to Produce High-strength and Corrosion Resistant Alloy for Patient-Specific Bioresorbable Bone Fixation Implants and Hardware
Project ID: D2016-43IP Status: Provisional Patent Application # 62/270,227Invention Description: Novel metallic alloy composition combined with a post-shaping heat-treatment process produces bioresorbable bone fixation hardware and implants. The technology produces stronger and less biocorrosive patient-specific devices than the base material. The ...
Biomimetic approach to deposit bone-like coating on PEEK and other materials to improve osteoconductivity in implants
Project ID: D2011-33IP Status: Patent Pending U.S and EuropeInvention Description: Novel method to prepare an implantable article comprised of a biocompatible substrate (polymeric or ceramic) to accept a very thin biocompatible, bioactive coating material to facilitate bio-ingrowth between the substrate and bone or cartilage tissue.Applications: Bo...
Amine-terminated Aptamer Functionalized SPR Sensor
Project ID: D2012-07 IP Status: Provisional Application Invention novelty and description: This novel invention describes sensors for target entities having at least one amine-terminated aptamer specific to the target entity. Aptamers are artificial oligonucleotides which can serve as antibody mimics because of their high affinity and selectivity ...
Highly sensitive portable technique for detecting wide variety of biological analytes
Project ID: PHYS00304 IP Status: Issued U.S. Utility Patent 8,143,072 Invention novelty and description: Novel technology offers a sensitive and broadly applicable system to detect magneto-optical and plasmon-like resonance properties of magnetic nanoparticles (MNP), dosed MNPs and biological analytes using optical or magneto-optical reflection, t...
Engineered Protein Tames Bleeding In Haemophiliacs and Targets Angiogenesis in Cancer
Project ID: D2007-12 U.S. Patent #8,211,858; Canada, European patents pending U.S. Patent #7,592,422; Canada, France, Germany, Netherlands, UK patents pending Novelty: Modified plasminogen activator inhibitor type I (PAI- 1) with significantly increased in vivo half-life and decreased activity to urokinase plasminogen activator, tissue plasminog...